The Science of Light Therapy
Taopatch® was created to combine the effects of low-intensity laser photobiomodulation, with a technology and support that allows ultra-weak and continuous administration, breaking the patterns that provided for repeated cycles of sessions at centers or the purchase of expensive and bulky instruments for home use as the only way of administering these therapies.
This brings advantages never seen before, since, especially in rehabilitation and neuroplasticity, it is the continuity of therapy that accelerates the recovery processes.
Each wavelength used to design Taopatch® has an immense scientific bibliography.
We list just a few referring to the main results that photobiomodulation has shown, for the treatment of several common disorders.
The scientific bibliography on light therapy counted over 60,000 studies when Taopatch® was born, today at the beginning of 2023 there are more than 135,000 scientific publications on the benefits of photobiomodulation for human health.
This immense scientific bibliography is divided into the main keywords (photobiomodulation, phototherapy, LLLT low level laser therapy, ULLLT, Redlight therapy, near, middle and far infrared therapy, photostimulation, bright light therapy, blu light therapy etc ...).
Most commonly used drugs do not boast such a large number of scientific studies. This makes light therapy and photobiomodulation not only a widely recommended therapy but also considered a therapy without side effects.
Diseases with Musculoskeletal Disorders
www.minervamedica.it/en/journals/europa-medicophysica/article.php?cod=R33Y2017N04A0603
Arthritis
pubmed.ncbi.nlm.ni.gov/1727843/
Bone Repair
pubmed.ncbi.nlm.nih.gov/25653816/
Brain health
pubmed.ncbi.nlm.nih.gov/25196192/
www.mdpi.com/2304-6732/6/3/77/htm
Circadian biology
www.ncbi.nlm.nih.gov/pmc/articles/PMC2717723/
www.ncbi.nlm.nih.gov/pmc/articles/PMC2290997/
www.ncbi.nlm.nih.gov/pmc/articles/PMC5863078/
Collagen
www.ncbi.nlm.nih.gov/pmc/articles/PMC5963836/
iopscience.iop.org/article/10.1143/JJAP.3.117/meta
research.qut.edu.au/pmbm/projects/understanding-and-exploring-piezoelectricity-in-collagen/
Diabetic neuropathy
www.ncbi.nlm.nih.gov/pmc/articles/PMC4639677/
www.liebertpub.com/doi/abs/10.1089/pho.2009.2680
Fat reduction
www.ncbi.nlm.nih.gov/pmc/articles/PMC5225499/
Gut-brain
link.springer.com/article/10.1007/s10103-018-2594-6
pubmed.ncbi.nlm.nih.gov/29890728/
pubmed.ncbi.nlm.nih.gov/27424097/
Hair growth
www.ncbi.nlm.nih.gov/pmc/articles/PMC3944668/
Immune system
www.ncbi.nlm.nih.gov/pmc/articles/PMC3643261/
www.ncbi.nlm.nih.gov/pmc/articles/PMC5215870/
pubmed.ncbi.nlm.nih.gov/21955546/
www.jstage.jst.go.jp/article/islsm/3/4/3_91-OR-23/_pdf
link.springer.com/article/10.1007/s10103-012-1129-9
www.aafp.org/pubs/afp/issues/2011/1215/p1412.html
Mechanisms
www.ncbi.nlm.nih.gov/pmc/articles/PMC5215870/
pubmed.ncbi.nlm.nih.gov/24379964/
https://pubmed.ncbi.nlm.nih.gov/38309304/
https://pubmed.ncbi.nlm.nih.gov/38307144/
https://www.sciencedirect.com/science/article/pii/S2666469023000386
Meridians
pubmed.ncbi.nlm.nih.gov/29103083/
www.ncbi.nlm.nih.gov/pmc/articles/PMC3838801/
Mitochondria
pubmed.ncbi.nlm.nih.gov/16124858/
www.ncbi.nlm.nih.gov/pmc/articles/PMC3316879/
medlineplus.gov/genetics/understanding/mutationsanddisorders/mitochondrialconditions/
https://www.sciencedirect.com/science/article/pii/S2666469023000386
https://pubmed.ncbi.nlm.nih.gov/30550048/
Muscle
link.springer.com/article/10.1007/s10103-017-2368-6
onlinelibrary.wiley.com/doi/abs/10.1002/jbio.201600176
www.ncbi.nlm.nih.gov/pmc/articles/PMC5026559/
Nervous system
www.ncbi.nlm.nih.gov/pubmed/23492552
www.ncbi.nlm.nih.gov/pubmed/20358337
pubmed.ncbi.nlm.nih.gov/24093608/
www.ncbi.nlm.nih.gov/pubmed/29890728
https://pubmed.ncbi.nlm.nih.gov/38600582/
https://arxiv.org/abs/1906.02501
Pain
jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0679-3
pubmed.ncbi.nlm.nih.gov/21725826/
pubmed.ncbi.nlm.nih.gov/16706688
pubmed.ncbi.nlm.nih.gov/18754533/
pubmed.ncbi.nlm.nih.gov/16979496/
pubmed.ncbi.nlm.nih.gov/23329239/
www.dovepress.com/use-of-low-intensity-laser-treatment-in-neuropathic-pain-refractory-to-peer-reviewed-fulltext-article-IJGM
pubmed.ncbi.nlm.nih.gov/20682161
https://pubmed.ncbi.nlm.nih.gov/34913330/
pubmed.ncbi.nlm.nih.gov/21290392/
www.sciencedirect.com/science/article/abs/pii/S1081120610632024
Skin
www.ncbi.nlm.nih.gov/pmc/articles/PMC4126803
www.ncbi.nlm.nih.gov/pmc/articles/PMC4745411 https://pubmed.ncbi.nlm.nih.gov/38674067/
https://onlinelibrary.wiley.com/doi/10.1002/jbio.202200257
https://pubmed.ncbi.nlm.nih.gov/22105015/
https://pubmed.ncbi.nlm.nih.gov/36310510/
https://pubmed.ncbi.nlm.nih.gov/21421326/
Stem Cells
laserfocusworld.com/test-measurement/research/article/16548173/photobiomodulation-regeneration-without-risk-lightenabled-tissue-repair
www.ncbi.nlm.nih.gov/pmc/articles/PMC4291821/
www.ncbi.nlm.nih.gov/pmc/articles/PMC4146146/
pubmed.ncbi.nlm.nih.gov/24871130/
pubmed.ncbi.nlm.nih.gov/21674545/
www.ncbi.nlm.nih.gov/pmc/articles/PMC6499560/
www.liebertpub.com/doi/abs/10.1089/pho.2016.4216?journalCode=pho
Teeth
medicalxpress.com/news/2014-05-coax-stem-cells-regrow-teeth.html
pubmed.ncbi.nlm.nih.gov/17052624/
pubmed.ncbi.nlm.nih.gov/21473840
www.newscientist.com/article/dn25649-forget-the-dentists-drill-use-lasers-to-heal-teeth
Toilet
pubmed.ncbi.nlm.nih.gov/20649429/
www.ncbi.nlm.nih.gov/pmc/articles/PMC6462613/
www.ncbi.nlm.nih.gov/pmc/articles/PMC4256027/
Wound healing
www.ncbi.nlm.nih.gov/pmc/articles/PMC5991292/
www.ncbi.nlm.nih.gov/pubmed/2541199
www.futuremedicine.com/doi/abs/10.2217/rme.15.82
pubmed.ncbi.nlm.nih.gov/11776448/
PMC9959862
Universities and Scientific Bodies that conduct research on Taopatch®, and Databases that collect and publish studies:




















Partnership with the San Raffaele University of Rome
We are proud to have started a prestigious partnership with the San Raffaele University of Rome, within which we have activated a PhD with an industrial path in the program "Innovative Lifestyle Interventions for Health Promotion" – XL Cycle.
This important collaboration consolidates our link with the academic world and confirms our commitment to scientific research and innovation, aimed at developing solutions dedicated to well-being and health.
PUBLISHED RESEARCH ON TAOPATCH®
Posture, Balance, Gait, and Motor Control
- Effects of nanotechnologies-based devices on postural control in healthy subjects
PubMed: https://pubmed.ncbi.nlm.nih.gov/28880050/
The Journal of Sports Medicine and Physical Fitness: https://www.minervamedica.it/en/journals/sports-med-physical-fitness/article.php?cod=R40Y2018N10A1418
- Effects of a nanotechnology-based application on balance control in hearing aid users
PubMed: https://pubmed.ncbi.nlm.nih.gov/41874075/
Audiology Research: https://www.mdpi.com/2039-4349/16/2/42 - Improvement of gait, balance and coordination after application of Taopatch® device European Journal of Translational Myology: https://openurl.ebsco.com/EPDB%3Agcd%3A5%3A149381/detailv2?sid=ebsco%3Aplink%3Ascholar&id=ebsco%3Agcd%3A169737136&crl=c&link_origin=scholar.google.com
- The impact of nanotechnologies on the range of motion in the cervical and lumbar regions: a pilot study
KNOWLEDGE – International Journal: https://ojs.ikm.mk/index.php/kij/article/view/7159
Morphology and Spinal Alignment
- Evaluation of Taopatch® effects on spine morphology
Research Gate: https://www.researchgate.net/publication/372240834
Multiple Sclerosis
- A new road to improve vitamin D and balance through Taopatch® and proprioceptive protocol in Multiple Sclerosis patients
PubMed: https://pmc.ncbi.nlm.nih.gov/articles/PMC9830399/
European Journal Of Translational Myology: https://www.pagepressjournals.org/index.php/bam/article/view/10774
- Taopatch® combined with home-based training protocol to prevent sedentary lifestyle and biochemical changes in MS patients during COVID-19 pandemic
PubMed: https://pmc.ncbi.nlm.nih.gov/articles/PMC8495370/
European Journal of Translational Myology: https://www.pagepressjournals.org/index.php/bam/article/view/9877
- Utilisation des dispositifs nanotechnologiques dans les pathologies dégénératives cérébrales – Étude prospective sur 28 patients atteints de sclérose en plaques
Hegel: https://shs.cairn.info/revue-hegel-2019-2-page-114
Sport, Performance, and Neuromuscular Physiology
- Metabolic and neuromuscular responses to high-intensity training with and without Taopatch® nanotechnology: a pilot randomized control study
Central European Journal of Sport Sciences and Medicine: https://bibliotekanauki.pl/articles/64153734
- From lab to track: the Taopatch® biomarker and performance detection technologies
Journal of Biological Research: https://www.pagepressjournals.org/jbr/article/view/12560/11869
Pain and Therapeutic Applications
- Acute effects of nanotechnological devices for the muscle and joint pain treatment
Springer Nature: https://link.springer.com/chapter/10.1007/978-3-031-63755-1_7
Sleep and Well-being
- Enhancing sleep quality: The impact of the “Repose Tao” Pillow with Taopatch® nanotechnology—A Pilot Study
PubMed: https://pubmed.ncbi.nlm.nih.gov/40700254/
Clocks and Sleep: https://www.mdpi.com/2624-5175/7/3/32
Dentistry and Periodontology
- Performance, balance and posture variations with Occlusal Splint and Taopatch® devices: a retrospettive cross-over study
PubMed: https://pubmed.ncbi.nlm.nih.gov/32744040/
The Journal of Sports Medicine and Physical Fitness: https://www.minervamedica.it/en/journals/sports-med-physical-fitness/article.php?cod=R40Y2021N02A0317
Europe PMC: https://europepmc.org/article/med/32744040
- Increase of keratinized peri-implant gingiva using dermal matrix and Taopatch® nanotechnology
Dental Tribune
- Gingival recessions of lower incisors treated with dermal matrix and Taopatch® nanotechnology
Dental Tribune
- Evaluation of the effectiveness of a new nanotechnological device as a support in the management of TMD in young and adult patient
PrePrints: https://www.preprints.org/frontend/manuscript/e0d0f29995bac43397ec487d3f9ba6e9/download_pub
CONFERENCE PRESENTATIONS AND POSTERS (AWAITING PUBLICATION)
Conference Presentation
- EMMS 2026: "Taopatch® for early fall-risk prevention in adults over 50: A pilot study on acute postural and gait adaptations" - San Raffaele University Rome
Bibliometric Poster
- Poster SISMES 2025: "State of the art on Taopatch® devices and photobiomodulation-based nanotechnologies: a bibliometric and narrative analysis" - University of Verona, San Raffaele University Rome
Dental Posters
- Poster SIDO 2025: "Effectiveness of Taopatch® devices in patients with bruxism" - University of Turin
- Poster EOS 2022: “Application of the Taopatch® biophotons in the daily orthodontic practice to increase patient's comfort and immediate pain relief in the area of the temporo-mandibular joint and the masticatory muscles” - Medical University Sofia, Faculty of Dental Medicine, Department of Orthodontics
- Poster SIOH 2017: "Nanotechnological supports (Taopatch®) in disabled subjects" - University of Turin, Dental School
Sport Poster
- Poster EMMS 2026: "Light-based neuromuscular performance modulation: acute effects of the nanotechnological device Taopatch® in young tennis players" - University of Verona e San Raffaele University, Rome
THESES AND ACADEMIC WORKS
Posture and Motor Control
- “Effects of Taopatch nanotechnology on lower limb biomechanics: comparison between experimental and placebo groups", Sapienza University of Rome – Study completed, awaiting publication.
- "Proprioceptive re-education and nanotechnologies: comparison of improvements in static and dynamic motor control in elderly subjects", University of Palermo – Study completed, awaiting publication.
Sport and Performance
- “Development and Performance in FIGC: Taopatch® Nanotechnology for Integrating Monitoring and Player Development in Futsal”, University of L’Aquila – Study completed, awaiting publication.
- "Influence of a gnathological bite and Taopatch nanotechnology on performance in martial arts athletes", University of Milan – Study completed, awaiting publication.
- "Taopatch: nanotechnology for advanced cycling Kore", University of Enna – Study completed, awaiting publication.
- "Taopatch® nanotechnology applied to sport: a biophysical approach to improving performance through neuromuscular balance (study on 16 cyclists)", University of Ferrara – Study completed, awaiting publication.
Clinical and Therapeutic Applications
- "Effectiveness of osteopathic treatment combined with Taopatch nanotechnological devices in patients with premenstrual syndrome (PMS)", Chinesis I.F.O.P. – Study completed, awaiting publication.
- "Taopatch® nanotechnology: neuromuscular and postural rebalancing through new methods and technologies – literature review", University of Naples Federico II – Study completed, awaiting publication.
Master’s and Advanced Studies
- Master in Sports Posturology: "Effects of TaoPatch® on posture", Kore University of Enna – Study completed, awaiting publication.
- Master in Posturology and Biomechanics: "Morphological changes of the spine in response to the tonic postural system with Taopatch® Pro nanotechnology", University of Palermo – Study completed, awaiting publication.
- Master in Clinical Posturology: "Integration between nanotechnology and posture", University of Pisa – Study completed, awaiting publication.
- Master in Posturology and Biomechanics: "Nanotechnologies and posture: from research to practical applications (healthy subjects and patients with Multiple Sclerosis)", University of Palermo.
- Master in Posturology: "Effects of nanotechnology devices applied on acupuncture points on postural control in healthy subjects", Sapienza University of Rome – Study completed, awaiting publication.
- Master in Posturology: "Can nanotechnology modify postural balance? Double-blind randomized study on competitive dancers", Sapienza University of Rome – Study completed, awaiting publication.
TESTS AND CERTIFICATIONS
- Anti-doping certification and confirmation of no chemical release, University of Milan
- Test of no chemical release and device stability, Kyoto Pharmaceutical Association