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The Science of Light Therapy

Taopatch® was created to combine the effects of low-intensity laser photobiomodulation, with a technology and support that allows ultra-weak and continuous administration, breaking the patterns that provided for repeated cycles of sessions at centers or the purchase of expensive and bulky instruments for home use as the only way of administering these therapies.


This brings advantages never seen before, since, especially in rehabilitation and neuroplasticity, it is the continuity of therapy that accelerates the recovery processes.

Each wavelength used to design Taopatch® has an immense scientific bibliography.

We list just a few referring to the main results that photobiomodulation has shown, for the treatment of several common disorders.

The scientific bibliography on light therapy counted over 60,000 studies when Taopatch® was born, today at the beginning of 2023 there are more than 135,000 scientific publications on the benefits of photobiomodulation for human health.

This immense scientific bibliography is divided into the main keywords (photobiomodulation, phototherapy, LLLT low level laser therapy, ULLLT, Redlight therapy, near, middle and far infrared therapy, photostimulation, bright light therapy, blu light therapy etc ...).

Most commonly used drugs do not boast such a large number of scientific studies. This makes light therapy and photobiomodulation not only a widely recommended therapy but also considered a therapy without side effects.

Diseases with Musculoskeletal Disorders
www.minervamedica.it/en/journals/europa-medicophysica/article.php?cod=R33Y2017N04A0603

Arthritis
pubmed.ncbi.nlm.ni.gov/1727843/

Bone Repair
pubmed.ncbi.nlm.nih.gov/25653816/

Brain health
pubmed.ncbi.nlm.nih.gov/25196192/
www.mdpi.com/2304-6732/6/3/77/htm

Circadian biology
www.ncbi.nlm.nih.gov/pmc/articles/PMC2717723/
www.ncbi.nlm.nih.gov/pmc/articles/PMC2290997/
www.ncbi.nlm.nih.gov/pmc/articles/PMC5863078/

Collagen
www.ncbi.nlm.nih.gov/pmc/articles/PMC5963836/
iopscience.iop.org/article/10.1143/JJAP.3.117/meta
research.qut.edu.au/pmbm/projects/understanding-and-exploring-piezoelectricity-in-collagen/

Diabetic neuropathy
www.ncbi.nlm.nih.gov/pmc/articles/PMC4639677/
www.liebertpub.com/doi/abs/10.1089/pho.2009.2680

Dosing
www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-23/issue-12/120901/Review-of-light-parameters-and-photobiomodulation-efficacy--dive-into/10.1117/1.JBO.23.12.120901.full?SSO=1

Fat reduction
www.ncbi.nlm.nih.gov/pmc/articles/PMC5225499/

Gut-brain
link.springer.com/article/10.1007/s10103-018-2594-6
pubmed.ncbi.nlm.nih.gov/29890728/
pubmed.ncbi.nlm.nih.gov/27424097/

Hair growth
www.ncbi.nlm.nih.gov/pmc/articles/PMC3944668/

Immune system
www.ncbi.nlm.nih.gov/pmc/articles/PMC3643261/
www.ncbi.nlm.nih.gov/pmc/articles/PMC5215870/
pubmed.ncbi.nlm.nih.gov/21955546/
www.jstage.jst.go.jp/article/islsm/3/4/3_91-OR-23/_pdf
link.springer.com/article/10.1007/s10103-012-1129-9
www.aafp.org/pubs/afp/issues/2011/1215/p1412.html

Mechanisms
www.ncbi.nlm.nih.gov/pmc/articles/PMC5215870/
pubmed.ncbi.nlm.nih.gov/24379964/
https://pubmed.ncbi.nlm.nih.gov/38309304/
https://pubmed.ncbi.nlm.nih.gov/38307144/
https://www.sciencedirect.com/science/article/pii/S2666469023000386

Meridians
pubmed.ncbi.nlm.nih.gov/29103083/
www.ncbi.nlm.nih.gov/pmc/articles/PMC3838801/

Mitochondria
pubmed.ncbi.nlm.nih.gov/16124858/
www.ncbi.nlm.nih.gov/pmc/articles/PMC3316879/
medlineplus.gov/genetics/understanding/mutationsanddisorders/mitochondrialconditions/
https://www.sciencedirect.com/science/article/pii/S2666469023000386
https://pubmed.ncbi.nlm.nih.gov/30550048/

Muscle
link.springer.com/article/10.1007/s10103-017-2368-6
onlinelibrary.wiley.com/doi/abs/10.1002/jbio.201600176
www.ncbi.nlm.nih.gov/pmc/articles/PMC5026559/

Nervous system
www.ncbi.nlm.nih.gov/pubmed/23492552
www.ncbi.nlm.nih.gov/pubmed/20358337
pubmed.ncbi.nlm.nih.gov/24093608/
www.ncbi.nlm.nih.gov/pubmed/29890728
https://pubmed.ncbi.nlm.nih.gov/38600582/ 
https://arxiv.org/abs/1906.02501

Pain
jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0679-3
pubmed.ncbi.nlm.nih.gov/21725826/
pubmed.ncbi.nlm.nih.gov/16706688
pubmed.ncbi.nlm.nih.gov/18754533/
pubmed.ncbi.nlm.nih.gov/16979496/
pubmed.ncbi.nlm.nih.gov/23329239/
www.dovepress.com/use-of-low-intensity-laser-treatment-in-neuropathic-pain-refractory-to-peer-reviewed-fulltext-article-IJGM
pubmed.ncbi.nlm.nih.gov/20682161
https://pubmed.ncbi.nlm.nih.gov/34913330/

Sinusitis
pubmed.ncbi.nlm.nih.gov/21290392/
www.sciencedirect.com/science/article/abs/pii/S1081120610632024

Skin
www.ncbi.nlm.nih.gov/pmc/articles/PMC4126803
www.ncbi.nlm.nih.gov/pmc/articles/PMC4745411 https://pubmed.ncbi.nlm.nih.gov/38674067/
https://onlinelibrary.wiley.com/doi/10.1002/jbio.202200257
https://pubmed.ncbi.nlm.nih.gov/22105015/
https://pubmed.ncbi.nlm.nih.gov/36310510/
https://pubmed.ncbi.nlm.nih.gov/21421326/

Stem Cells
laserfocusworld.com/test-measurement/research/article/16548173/photobiomodulation-regeneration-without-risk-lightenabled-tissue-repair
www.ncbi.nlm.nih.gov/pmc/articles/PMC4291821/
www.ncbi.nlm.nih.gov/pmc/articles/PMC4146146/
pubmed.ncbi.nlm.nih.gov/24871130/
pubmed.ncbi.nlm.nih.gov/21674545/
www.ncbi.nlm.nih.gov/pmc/articles/PMC6499560/
www.liebertpub.com/doi/abs/10.1089/pho.2016.4216?journalCode=pho

Teeth
medicalxpress.com/news/2014-05-coax-stem-cells-regrow-teeth.html
pubmed.ncbi.nlm.nih.gov/17052624/
pubmed.ncbi.nlm.nih.gov/21473840
www.newscientist.com/article/dn25649-forget-the-dentists-drill-use-lasers-to-heal-teeth

Toilet
pubmed.ncbi.nlm.nih.gov/20649429/
www.ncbi.nlm.nih.gov/pmc/articles/PMC6462613/
www.ncbi.nlm.nih.gov/pmc/articles/PMC4256027/

Wound healing
www.ncbi.nlm.nih.gov/pmc/articles/PMC5991292/
www.ncbi.nlm.nih.gov/pubmed/2541199
www.futuremedicine.com/doi/abs/10.2217/rme.15.82
pubmed.ncbi.nlm.nih.gov/11776448/
PMC9959862

Some studies and research conducted with our nanotechnology


  • A new road to improve vitamin D and balance through Taopatch® and proprioceptive protocol in Multiple Sclerosis patients
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC9830399/

  • Taopatch® combined with home-based training protocol to prevent sedentary lifestyle and biochemical changes in MS patients during COVID-19 pandemic
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC8495370/

  • Performance, balance and posture variations with Occlusal Splint and Taopatch® devices: a retrospective cross-over study
  • pubmed.ncbi.nlm.nih.gov/32744040/

  • Effects of nanotechnologies-based devices on postural control in healthy subjects
  • pubmed.ncbi.nlm.nih.gov/28880050/

  • Acute Effects of Nanotechnological Devices for the Muscle and Joint Pain Treatment
  • link.springer.com/chapter/10.1007/978-3-031-63755-1_7

  • Gum recessions of lower incisors treated with dermal matrix and with nanotechnology Taopatch®
  • https://s1.htmltojpg.com/rx/pdf_split/

  • Evaluation of Taopatch® effects on spine morphology
  • https://www.researchgate.net/publication/372240834_Evaluation_Of_TaopatchR_Effects_On_Spine_Morphology

  • Improvement of gait, balance and coordination after application of Taopatch® device 
  • https://openurl.ebsco.com/EPDB%3Agcd%3A12%3A10349884/detailv2?sid=ebsco%3Aplink%3Ascholar&id=ebsco%3Agcd%3A169737136&crl=c&link_origin=scholar.google.com

  • Utilisation des dispositifs nanotechnologiques dans les pathologies dégénératives cérébrales Étude prospective sur 28 patients atteints de sclérose en plaques
  • https://shs.cairn.info/revue-hegel-2019-2-page-114?lang=fr

  • From lab to track: the Taopatch® biomarker and performance detection technologies, University of Palermo, San Raffaele University of Rome, University of Catania, published in the Journal of Biological Research

  • Anti-Doping and Non-Release Certification, University of Milan, Department of Pharmaceutical Sciences, Chemical-Toxicological Analysis Laboratory

  • No chemical release or mass loss testing by the Taopatch® device and F.A.S.I.Q.U.E., Kyoto Pharmaceutical Association

  • MFPRM poster: "Evaluation of Taopatch® effects on spine morphology", University of Palermo

  • EOS poster: "Application of the Taopatch® biophotons in the daily orthodontic practice to increase patient's comfort and immediate pain relief in the area of the temporo-mandibular joint and the masticatory muscles", Medical University Sofia, Faculty of Dental Medicine, Department of Orthodontics

  • SIDO poster: "The usage of the human upgrade device Taopatch® in the facial region in adults and children", Medical University Sofia, Faculty of Dental Medicine, Department of Orthodontics

  • SIOH poster: "Nanotechnological supports (Taopatch®) in people with disabilities", University of Turin, Dental School
  • Poster-SIOH-Utilizzo-della-nanotecnologia-Taopatch%C2%AE-per-cure-odontoiatriche-in-soggetti-HCP-2017-1.pdf

  • Thesis "Influence of a gnathological bite and TaoPatch nanotechnology on the performance of athletes practicing martial arts", University of Milan

  • Thesis "Taopatch: Nanotechnology for Cutting-edge Cycling",  University of Enna "Kore"

  • Master's thesis "Effects of the TaoPatch® device on posture", University of Enna "Kore"

  • Thesis "Taopatch® nanotechnology applied to sport. A biophysical approach capable of improving performance through a rebalancing of the neuromuscular system: practical application on 16 cyclists", University of Ferrara

  • Thesis "Efficacy of osteopathic treatment associated with Taopatch nanotechnological devices in patients with premenstrual syndrome (PMS)", Chinesis I.F.O.P. - Institute of Training in Osteopathy and Posturology

  • Thesis "Taopatch® nanotechnology neuro-muscular and postural rebalancing with new methods and technologies", University of Naples Federico II

  • Master's Degree in Posturology and Biomechanics "Morphological changes of the spine in response to the postural tonic system with Taopatch® Pro nanotechnology", University of Palermo

  • Master of Clinical Posturology "Integration between nanotechnology and posture", University of Pisa

  • Master in Posturology and Biomechanics "Nanotechnologies and posture: From research to practical applications, "Applications on healthy subjects and with non-specific symptoms", "Applications on patients with Multiple Sclerosis", University of Palermo
  • https://www.researchgate.net/profile/Giuseppe-Messina-4/publication/319623157_Nanotecnologie_e_Postura/links/59c2c3360f7e9b21a82aa35b/Nanotecnologie-e-Postura.pdf

  • Master's Degree in Posturology "Effects of nanotechnology devices, applied to a combination of acupoints, on postural control in healthy subjects", Sapienza University of Rome

  • Master's Degree in Posturology "Can nanotechnology modify postural balance? Randomized double-blind study on a group of competitive dancers", Sapienza University of Rome

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